botulinum toxin for treatment of blepharospasm and hemifacial spasm

Botulinum a toxin treatment of hemifacial spasm and blepharospasm.

We studied the effects of botulinum A toxin in 101 patients with hemifacial spasm and 11 patients with blepharospasm in an open trial and double blind manner. All patients in the open trial and 6 patients in the double blind trial improved after the first injection of botulinum toxin. There was no improvement with placebo. The peak effect ranged from one to 6 days after injection and mean peak ...

Blepharospasm and hemifacial spasm: Long-term treatment with botulinum toxin

Blepharospasm and hemifacial spasm: long-term treatment with botulinum toxin.

INTRODUCTION Our purpose is to describe the demographic, clinical and therapeutic characteristics of patients with blepharospasm (BS) and hemifacial spasm (HFS) in treatment with botulinum toxin type A (BtA). PATIENTS AND METHODS Retrospective analysis of patients diagnosed with BS or HFS and treated with BtA in the Neurology Department at Complejo Asistencial de Segovia between March 1991 an...

Botulinum toxin A in blepharospasm and hemifacial spasm.

We report the first Indian experience of botulinum toxin A in the treatment of blepharospasm and hemifacial spasm. Sixteen patients, 7 with essential blepharospasm, 5 with Meige syndrome and 4 with hemifacial spasm received botulinum toxin A injection. One patient received 3 courses of injections, 2 received 2 courses and the rest received only one course. The effect was observed after a latent...

Botulinum toxin type B in blepharospasm and hemifacial spasm.

Botulinum neurotoxins (BTXs) inhibit the presynaptic release of acetylcoline causing a chemical denervation that results in sustained muscle weakness and have been used in the past 20 years to induce selective blocking of hyperactive striatal (and smooth) muscles. All the different seven serotypes of BTXs have in common the mechanism of action (block of the neuroexocytosis machinery inside the ...

Botulinum toxin type B in blepharospasm and hemifacial spasm

Botulinum neurotoxins (BTXs) inhibit the presynaptic release of acetylcoline causing a chemical denervation that results in sustained muscle weakness and have been used in the past 20 years to induce selective blocking of hyperactive striatal (and smooth) muscles. All the different seven serotypes of BTXs have in common the mechanism of action (block of the neuroexocytosis machinery inside the ...